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ONCODEcipher BRCA1/2 Germline NGS & MLPA Panel

Product Description:

NGS and MLPA panel targeting germline BRCA 1 & 2 mutations with 100% coverage including SNV, small InDels, large deletions & duplications, and large genomic rearrangement (LGR) to identify the risk of hereditary breast, ovarian, prostate, pancreatic cancers; and to seek for treatment options.

Genes Covered -- 100% coverage of BRCA 1 & 2 germline mutations

Technique:

Next Generation Sequencing (NGS) & Multiplex Ligation-Dependent Probe Amplification (MLPA)

Test Methodology:

NGS: DNA extracted from blood is subjected to amplification-based library preparation and massively parallel sequencing. Sequencing analysis is performed using proprietary bioinformatics pipelines.

MLPA: DNA extracted from blood is subjected to Multiplex Ligation-Dependent Probe Amplification. Fluorescent labelled amplicons are separated and quantified by capillary electrophoresis.

Specimen Requirements:

3ml Blood in EDTA tube(s)

TAT

Turn Around Time:

12-15 working days

shipment_requirement

Shipment Requirement:

Keep specimen at room temperature. DO NOT ship on ice or dry ice or expose to direct sunlight.

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