ONCODEcipher BRCA1/2 Germline NGS & MLPA Panel
Product Description:
NGS and MLPA panel targeting 31 germline genes mutations with 100% coverage including SNV, small InDels, large deletions & duplications, and large genomic rearrangement (LGR) to identify the risk of hereditary cancers; and to seek for treatment options.
Highlighted Genes -- Somatic BRCA1 & BRCA2, MLH1, MSH2, MSH6, TP53, etc.
Technique:
Next Generation Sequencing (NGS) & Multiplex Ligation-Dependent Probe Amplification (MLPA)
Test Methodology:
NGS: DNA extracted from blood is subjected to amplification-based library preparation and massively parallel sequencing. Sequencing analysis is performed using proprietary bioinformatics pipelines.
MLPA: DNA extracted from blood is subjected to Multiplex Ligation-Dependent Probe Amplification. Fluorescent labelled amplicons are separated and quantified by capillary electrophoresis.
Specimen Requirements:
3ml Blood in EDTA tube(s)
Turn Around Time:
12-15 working days
Shipment Requirement:
Keep specimen at room temperature. DO NOT ship on ice or dry ice or expose to direct sunlight.