ONCODEduce AML Combo (Mutation & Fusion) NGS Panel
Comprehensive package for AML for the diagnosis, prognostic, and therapy selection targeting genes mutations (DNA mutation) in hotspot regions/selected exons of 13 genes commonly mutated in AML, and the commonest rearrangements (RNA fusions) in 11 genes implicated in AML.
Highlighted Genes -- Mutation: FLT3-ITD & TKD, NPM1, CEBPA, IDH1/2, KIT, RUNX1, TP53, etc.; Fusion: RUNX1, CBFB, RARA, BCR, ABL1, MLL/KMT2A, etc.;
Next Generation Sequencing (NGS)
DNA and RNA extracted from blood/ marrow/ aspirate smears is subjected to amplification-based library preparation and massively parallel sequencing. Sequencing analysis is performed using commercial bioinformatics pipelines and annotation is done using proprietary and public databases.
6ml of Blood or Marrow Aspirate in EDTA tube or
4 aspirate smears with adequate cellularity
Turn Around Time:
10 working days
Keep specimen at room temperature. DO NOT ship on ice or dry ice or expose to direct sunlight.