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ONCODEduce AML Combo (Mutation & Fusion) NGS Panel

Product Description:

Comprehensive package for AML for the diagnosis, prognostic, and therapy selection targeting genes mutations (DNA mutation) in hotspot regions/selected exons of 13 genes commonly mutated in AML, and the commonest rearrangements (RNA fusions) in 11 genes implicated in AML.

Highlighted Genes -- Mutation: FLT3-ITD & TKD, NPM1, CEBPA, IDH1/2, KIT, RUNX1, TP53, etc.; Fusion: RUNX1, CBFB, RARA, BCR, ABL1, MLL/KMT2A, etc.;


Next Generation Sequencing (NGS)

Test Methodology:

DNA and RNA extracted from blood/ marrow/ aspirate smears is subjected to amplification-based library preparation and massively parallel sequencing. Sequencing analysis is performed using commercial bioinformatics pipelines and annotation is done using proprietary and public databases.

Specimen Requirements:

6ml of Blood or Marrow Aspirate in EDTA tube or
4 aspirate smears with adequate cellularity


Turn Around Time:

10 working days


Shipment Requirement:

Keep specimen at room temperature. DO NOT ship on ice or dry ice or expose to direct sunlight.

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