Patient was on conventional cancer treatment until lung metastasis was discovered, his physician has opted for immunotherapy as treatment option. However, due to high treatment cost, the patient’s family would like to explore more treatment options with ONCODE.

ONCODEcipher report has shown that patient is BRAF V600E positive, which makes patient an eligible candidate for enrolment into clinical trial. New drug combinations have been prescribed to the patient by his physician with zero expenses for the medication.

Conclusion: Patient is now doing well with the new drug combination with minimum side effects.

Patient’s condition was worsening despite on chemotherapy, patient had engaged with ONCODE for a comprehensive liquid biopsy genomic profiling, which includes BRCA gene testing. ONCODEcipher report has shown that patient is positive for pathogenic BRCA2 and AKT1, which makes patient a suitable candidate for PARP inhibitors treatment and clinical trial candidate for AKT1 inhibitor. With AKT1 mutation, endocrine therapy is less likely to be beneficial for this patient, thus endocrine therapy was avoided.


Conclusion: Patient is now waiting to receive approval for enrolment into new PARP inhibitor drug trial.

Physician has ordered an ONCODEduce test, report shows that the patient manifests FLT3-ITD, KIT and CEBPA mutations.
ONCODEduce report has not only summarised treatment options including bone marrow transplant. With allele frequency information (one of important clues to check for hereditary factor), all family members of patient were recommended by physician to check for hereditary gene mutation. This is to rule out the risk factor of disease development in family members, as well as exploring bone marrow transplant as one of the treatment options for this patient. All family members were detected negative for the gene mutations and thus there is no risk factors of developing the same cancer as patient due to the said genes.


Conclusion: This patient has gone for bone marrow transplant, donated by her family member.